Soluble receptor against lupus?
نویسندگان
چکیده
منابع مشابه
Serum soluble interleukin-2 receptor alpha in systemic lupus erythematosus.
INTRODUCTION This study aimed at determination of circulating soluble interleukin-2 receptor (IL-2 R) alpha in the sera of patients with systemic lupus erythematosus (SLE) and correlating the level of expression of these receptors with the SLE disease activity. MATERIALS AND METHODS The study included 55 patients with SLE and 20 healthy volunteers as controls. The following investigations wer...
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Mice were immunized with 1 to 3 micrograms of cytoplasmic estrogen receptor fragment purified from human myometrium by affinity chromatography. Two RE-antibody-secreting clones were detected from one fusion that were capable of precipitating cytosol RE. Monoclonal antibody D5 (subclass IgG1) reacts with an antigen that is related to RE from immunoprecipitation studies but which can be separated...
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Mice were immunized with 1 to 3 fig of cytoplasmic estrogen receptor fragment purified from human myometrium by affinity chromatography. Two RE-antibody-secreting clones were de tected from one fusion that were capable of precipitating cytosol RE. Monoclonal antibody D5 (subclass Igd) reacts with an antigen that is related to RE from immunoprecipitation studies but which can be separated from t...
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Nervous system dysfunction may occur in as many as 80% of patients with Systemic Lupus Erythematous (SLE) at some point in their disease course. Upregulation of adhesion molecules has been linked to acute SLE-related disease activity and chronic damage. We evaluated the relationship between soluble adhesion molecule levels and neuropsychiatric lupus (NPSLE) manifestations using the American Col...
متن کاملSerum soluble interleukin 7 receptor is strongly associated with lupus nephritis in patients with systemic lupus erythematosus.
BACKGROUND The soluble form of the interleukin 7 receptor (sIL-7R) is produced by fibroblasts after stimulation with proinflammatory cytokines. Increased sIL-7R serum and synovial fluid levels were recently demonstrated in patients with rheumatoid arthritis. OBJECTIVES To investigate whether sIL-7R production is dysregulated in systemic lupus erythematosus (SLE), and whether this correlates w...
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ژورنال
عنوان ژورنال: Nature Biotechnology
سال: 2000
ISSN: 1087-0156,1546-1696
DOI: 10.1038/76367